I am confident the journal will upgrade itself well and be able to attain a good impact factor and would therefore become one of the leading journals in the world in the. Each year research scientists have noticed a rise in the number of congresses being held in this field. Immune modulatory mesenchymal stem cells derived from human embryonic stem cells through a trophoblastlike stage. Stably transduced human ipscderived neural progenitors show inducible, reversible expression of gdnf, a fluorescent reporter protein, and luciferase in vitro and following transplantation into the mouse brain. Jun 24, 2015 factors released following stem cell transplantation therapeutically impact serious burns. From the 2000s, clinical applications of stem cells significantly increased. International journal of stem cells rg journal impact. However, this drug has numerous side effects, which include impaired healing and regeneration after injuries or tissue damages. Table of contents 2015 page 10 stem cells international. Stem cell research and medicine mainly focuses on the basic research, clinical studies and translational research in the fields of stem cell biology and regenerative medicine. To reauthorize the stem cell therapeutic and research act of 2005, and for other purposes. World journal of stem cells baishideng publishing group.
Alzheimers disease ad represents arguably the most significant social, economic, and medical crisis of our time. Whether arms tumor cells can fuse with normal myogenic progenitors such as skeletal muscle stem cells satellite cells or myoblasts is unknown, as is the biological effect of fusion events if. With a focus on stem cells of all tissue types and their potential therapeutic applications, the journal provides clinical, basic, and translational scientists with cuttingedge research and findings. Apr 26, 2018 svendsen, breunig, and colleagues generated a plasmid containing a tetracycline transactivator and a response element expressing dual reporters and gdnf. This cytokine plays an important role in hematopoiesis formation of blood cells, spermatogenesis, and melanogenesis. Researchers working on embryonic like stem cells from adult donors. Factors released following stem cell transplantation. Cell differentiation is the process by which the cells increase their number.
But the limited supply of stem cells has paused the progress on many fronts. It covers contemporary and emerging areas in stem cells, including embryonic and adult stem cells, and related lineage and cloning issues. Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Characterized by progressive neurodegenerative pathology, ad is first and foremost a condition of neuronal and synaptic loss. The journal is essential reading for all researchers and clinicians involved in stem cells research. Stem cells translational medicine wiley online library. Stem cells international publishes papers in all areas of stem cell biology and applications. First licensed stem cell therapy for als biopharma. Nonetheless, the isolation of pluripotent mscs using specific markers remains a challenge.
Stem cells impact factoromics internationalclinical case. The journal publishes basic, translational, and clinical research, including animal models and clinical trials. Alongside neuronatar, corestem is also progressing the clinical development of stem cell therapies for lupus nephritis and multiple system atrophy both phase 1 and a pipeline of preclinical candidates. By bridging stem cell research and helping speed translations of emerging lab discoveries into clinical trials, stem cells translational medicine will help move applications of these critical investigations closer to accepted best practices and ultimately improve patient. Stem cells impact factor, if, number of article, detailed information and journal factor. Stem cells are distinguished from other cell types by two important characteristics. Cancer stem cells cscs are a class of pluripotent cells that have been observed in most types of solid and hematologic cancers. Specialized cytonemes induce selforganization of stem cells. Specifically, we are trying to learn how macrophages impact the release of of using a macrophage activating factor maf, such as lymph. Stem cells translational medicine works to advance the clinical utilization of stem cell molecular and cellular biology. May 12, 2017 alzheimers disease ad represents arguably the most significant social, economic, and medical crisis of our time. Impact factor of journal stem cells 2016 2015 2014 impact. Corrigendum to the effect of adiposederived stem cells on wound healing. For example, elaine and her team found that they could cause excessive hair follicles to form by specifically expressing an activated.
Alzheimers disease, dementia, and stem cell therapy. Updated list of high journal impact factor stem cell journals. We describe escgenerated cytonemes that react to selfrenewalpromoting. Most downloaded stem cell research articles elsevier. Wolvetang and colleagues used crisprcas9 technologies to manipulate the copy number and expression of the amyloid precursor protein app gene in down syndrome and corresponding euploid pluripotent stem cells. Stem cells and development is globally recognized as the trusted source for. Articles published in wjsc are highquality, basic and clinical, influential research articles by established academic authors as. Wjsc accepts both solicited and unsolicited manuscripts. Octamerbinding transcription factor 4 oct4, nanog, sexdetermining region y box 2 sox2, and kruppellike factor 4 klf4 are expressed only at low levels in hucmscs, suggesting that mscs are primitive stem cells, between escs and adult mature cells. I did a poll below on the best stem cell journals overall and the results of our readers were overwhelming. Many questions about how stem cells communicate with neighboring cells and selforganize to initiate tissue formation remain unanswered. First licensed stem cell therapy for als biopharma dealmakers. Myeloproliferative neoplasm mpn stem cells are defined as a clonal population of rare cells within the bone marrow that harbor an mpninitiating somatic mutation, are capable of indefinite selfrenewal, and that, through a combination of cellintrinsic and cellextrinsic effects undergo clonal expansion. The journal covers all aspects of stem cells embryonic stem cellsinduced pluripotent stem.
Scf can exist both as a transmembrane protein and a soluble protein. This process has involvement of huge number of genes which are like double edged swords as they also trigger cancer. Jul 28, 2015 the percentage of cscs had a prognostic impact. Stem cell therapeutic and research reauthorization act of. Characterization and therapeutic application of mesenchymal. Impact factor of stem cells international research. Stem cells and development is globally recognized as the trusted source for critical, even controversial coverage of emerging hypotheses and novel findings. Stem cell transplantation has the long history of more than 50 years from the first bone marrow transplantation in 1957. Mouse ovarian very small embryoniclike stem cells resist. By bridging stem cell research and helping speed translations of emerging lab discoveries into clinical trials, stem cells translational medicine will help move applications of these critical investigations closer to accepted best practices and ultimately. Repopulation and regeneration of depleted neuronal circuitry by exogenous stem cells is therefore a rational.
Impact of cell composition and geometry on human induced pluripotent stem cells derived engineered cardiac tissue. Aug 21, 2019 alongside neuronatar, corestem is also progressing the clinical development of stem cell therapies for lupus nephritis and multiple system atrophy both phase 1 and a pipeline of preclinical candidates. With a focus on stem cells of all tissue types and their potential therapeutic applications, the journal provides clinical, basic, and translational scientists with cuttingedge research. Jun 25, 2015 they seek and destroy foreign intruders to include cancer cells, viruses, and bacteria. Submissions to stem cell research, may cover all aspects of stem cells, including embryonic stem cells, tissuespecific stem cells, cancer stem cells, developmental studies, genomics and translational research. Stem cell research is dedicated to publishing highquality manuscripts focusing on the. Alzheimers disease, dementia, and stem cell therapy stem.
They demonstrate that app modulates the expression of a surprisingly large cohort of genes and dictates a. Impact factor of journal stem cells 2016 2015 2014. Different mechanisms contribute to intratumor heterogeneity, including genetic mutations, the microenvironment, and the existence of subpopulations of cancer cells with increased renewal capacity and the ability to recapitulate the heterogeneity found in primary tumors, which are referred to as cancer stem cells cscs. It suggests negative effects of morphine on stem cells which are responsible for tissue regeneration. Very small embryoniclike stem cells vsels are major pluripotent stem cells described in human and mouse. Novel method produces lifesaving t cells from mesenchymal stromal cells new study. Stem cells is read and written by clinical and basic scientists whose expertise encompasses the rapidly expanding fields of stem and progenitor cell biology. Repopulation and regeneration of depleted neuronal circuitry by exogenous stem cells is therefore a rational therapeutic strategy. Impact factor of stem cells american research journals. An emerging therapeutic approach suggested to have potential to target malignant gliomas has been based on the use of multipotent mesenchymal stem cells mscs, either unmodified or engineered to deliver anticancer therapeutic agents, as these. Stem cells rg journal impact rankings 2018 and 2019.
Armed with the power of mouse genetics, the fuchs lab identified skin phenotypes that impacted hair follicle development and regeneration figure 1a. Stably transduced human ipscderived neural progenitors show inducible, reversible expression of gdnf, a fluorescent reporter protein, and luciferase in vitro and following transplantation into the. Citescore values are based on citation counts in a given year e. In press, journal preproof, available online 8 may 2020. The journal publishes key, wellcontrolled advances in stem cell clinical trials and mechanismbased manuscripts with definitive conclusions.
Chief editor, professor li, has a background in cardiac stem cell transplantation, using young stem. Stem cell research impact factor archives the niche. Stem cell factor also known as scf, kitligand, kl, or steel factor is a cytokine that binds to the ckit receptor. Myeloproliferative neoplasm stem cells blood american. Mouse ovarian very small embryoniclike stem cells resist chemotherapy and retain ability to initiate oocytespecific differentiation kalpana sriraman, phd, deepa bhartiya, phd, sandhya anand, msc, and smita bhutda, msc. Therefore, we studied the impact of morphine on the. The impact of morphine on the characteristics and function. Morphine is an analgesic drug therapeutically administered to relieve pain. If you need to publish your latest exciting stem cell manuscript or are wanting to read some stem cell and regenerative medicine articles, you nee.
Cscs have been shown in numerous cancer models to be involved in tumor development, cell proliferation, and metastatic dissemination, while possessing a capacity for sustained selfrenewal. This study was undertaken to investigate stem cells in adult mouse ovary, the effect of chemotherapy on them and their potential to differentiate into germ cells. Svendsen, breunig, and colleagues generated a plasmid containing a tetracycline transactivator and a response element expressing dual reporters and gdnf. Download templates and learn how to submit lab resource articles. Table of contents stem cells international hindawi. Glioblastoma gbm is a highly aggressive primary brain cancer, for which curative therapies are not available. Stem cells are considered as a boon for mankind in the medical world. Impact of cell composition and geometry on human induced pluripotent stem cellsderived engineered cardiac tissue. Stem cell research is dedicated to publishing highquality manuscripts focusing on the biology and applications of stem cell research.
Stem cells international table of contents 2015 stem cells international publishes papers in all areas of stem cell biology and applications. We uncovered mechanisms employed by embryonic stem cells escs and trophoblast stem cells tscs to coform embryolike structures. Journal citation reports clarivate analytics, 2019 5year impact factor. Wang x, lazorchak as, song l, li e, zhang z, jiang b. Factors released following stem cell transplantation therapeutically impact serious burns.